Other Skin, Phase III
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants With High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
Volunteers
Health Professionals
What is the purpose of this trial?
This is a randomized, double-blind, study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing recurrence free survival (RFS).
- Trial withMerck Sharp & Dohme LLC
- Ages18 years and older
- GenderBoth
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Principal Investigator
Sub-Investigators
- Last Updated11/14/2023
- Study HIC#2000024768